Sequence Variations within Protein Families are Linearly Related to Structural Variations
نویسندگان
چکیده
منابع مشابه
Sequence variations within protein families are linearly related to structural variations.
It is commonly believed that similarities between the sequences of two proteins infer similarities between their structures. Sequence alignments reliably recognize pairs of protein of similar structures provided that the percentage sequence identity between their two sequences is sufficiently high. This distinction, however, is statistically less reliable when the percentage sequence identity i...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2002
ISSN: 0022-2836
DOI: 10.1016/s0022-2836(02)00971-3